A film that would serve as something of a prequel to Ridley Scott's seminal 1979 film Alien has been in the works for years. With Prometheus, the wait was all worth it as Damon Lindelof (who wrote for MTV's Undressed and was a former Nicholl semi-finalist) and John Spaihts (The Darkest Hour) weave a spot-on cheesy science-fiction script that only Ridley Scott could make work outside of the 70s. Charlize Theron as Meredith Vickers, the director of the ship Prometheus, is, hands down, given all of the best lines. In fact, she may be the best part of Prometheus, especially if you see the genius in the dominatrix-like delivery of her lines (e.g. "I think there might be some confusion about the nature of our relationship.").
The mission of Prometheus is simple: Follow a star map found by archaeologists Elizabeth Shaw (Noomi Rapace) and Charlie Holloway (Logan Marshall-Green, not to be confused with Tom Hardy) to the moon known as LV-223. Funded by Peter Weyland (Guy Pearce, who still looks pretty hot as a fossil) of the Weyland Corp., the intent of the mission is to accept what is presumed as an invitation from their "makers" to learn more about the forerunners that created them. Guided by an android called David (Michael Fassbender, who can twerk an Aryan appearance quite well), the ship is run tightly by Meredith, who, in a creepy scene toward the end of the film, we learn is the daughter of Weyland.
Everything seems to be going smoothly (doesn't it always?) until Charlie, Elizabeth, and their fellow explorers come across a number of stone cylinders, the corpse of an alien, and a decapitated head. Unnerved by the storm that occurs immediately after the cylinders start leaking, the crew makes its way back to the ship, but not before David steals one of the cylinders. Once back on Prometheus, the head found in the cave is dissected and found to have human DNA. Meanwhile, David puts his latent plan into motion by extracting the liquid from the cylinder and lacing Charlie's drink with it. Later that night, Charlie sleeps with Elizabeth, unaware of what their union foretells.
Outside of Prometheus, Charlie, Fifield (Sean Harris), and Millburn (Rafe Spall) are attacked by aliens resembling snakes and attempt to make their way back onto the ship. The infection from the liquid, at this point, has infected Charlie at an alarming rate, and, seeing the nature of his condition, Meredith refuses to let him onto the ship, instead dousing him with fire and killing him. Though Millburn has also been killed, Fifield mutates into something inhuman and tries to attack everything in his path before being quelled.
Already traumatized by the death of Charlie, Elizabeth must also grapple with the news that she is pregnant with an alien spawn in spite of being sterile. In typical thug, Girl With the Dragon Tattoo style, Elizabeth hops into a machine that plucks the alien from her stomach and then staples it shut, just in time for her to escape from her own "child." It's really quite foul to watch, but at the same time, the most memorable and iconic scene from the movie (unless you're a dude, in which case, it's Charlize Theron doing push-ups).
The intense urgency of Prometheus merely elevates from this moment forth, as Elizabeth struggles to understand why mankind's creators would give them life only to concoct a biological weapon intended to destroy them. Determined to figure out the reason, the film concludes with Elizabeth using what is left of David (his detached head) to get another one of the Engineer's ships to work so that she can go to their planet and personally confront them. In other words, get ready for another Ridley Scott Alien-tinged movie. Though, of course, no one will ever hold a candle to Sigourney Weaver.